Dysregulation of hepatic microRNA expression profiles with Clonorchis sinensis infection

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Dysregulation of hepatic microRNA expression profiles with Clonorchis sinensis infection

BACKGROUND Clonorchiasis remains an important zoonotic parasitic disease worldwide. The molecular mechanisms of host-parasite interaction are not fully understood. Non-coding microRNAs (miRNAs) are considered to be key regulators in parasitic diseases. The regulation of miRNAs and host micro-environment may be involved in clonorchiasis, and require further investigation. METHODS MiRNA microar...

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BACKGROUND The objective of this study was to analyze gallbladder stones for direct evidence of a relationship between Clonorchis sinensis infection and gallbladder stones formation. METHODOLOGY We investigated one hundred eighty-three gallbladder stones for the presence of Clonorchis sinensis eggs using microscopy, and analyzed their composition using Fourier transform infrared spectroscopy....

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Acute cholecystitis associated with Clonorchis sinensis infection

Clonorchis sinensis is one of the most common causes of trematodiasis that is caused by the ingestion of raw fish contaminated with infective cysts. The adult flukes are predominantly present in the intrahepatic bile ducts, but occasionally they may be found in the pancreatic duct and extrahepatic bile ducts. The clinical manifestations depend on the number of flukes, the period of infestation,...

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Hepatic iron overload is associated with hepatocyte apoptosis during Clonorchis sinensis infection

BACKGROUND Hepatic iron overload has been implicated in many liver diseases; however, whether it is involved in clonorchiasis remains unknown. The purpose of this study is to investigate whether Clonorchis sinensis (C. sinensis) infection causes hepatic iron overload, analyze the relationship between the iron overload and associated cell apoptosis, so as to determine the role of excess iron pla...

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Loffler’s Syndrome Associated with Clonorchis Sinensis Infestation

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2016

ISSN: 1471-2334

DOI: 10.1186/s12879-016-2058-1